Article
Genotype distribution of norovirus around the emergence of Sydney_2012 and the antigenic drift of contemporary GII.4 epidemic strains.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2015
Zhang Jun, Shen Zhen, Zhu Zhaoqin, Zhang Wanju, Chen Huifen, Qian Fangxing, Chen Haili, Wang Gang, Wang Moying, Hu Yunwen, Yuan Zhenghong
Abstract excerpt
BACKGROUND: The pattern of epochal evolution of NoV is ongoing, while novel GII.4 variants emerge and cause new pandemics. Since, the emergence in March 2012, Sydney_2012 had replaced GII.4-2009 as the primary NoV strain in most countries in the northern hemisphere by November 2012. OBJECTIVES: To determine the genotype distribution around the emergence of Sydney_2012 and to investigate the underlying evolution...
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