Article
Arsenic metabolism, N6AMT1 and AS3MT single nucleotide polymorphisms, and their interaction on gestational diabetes mellitus in Chinese pregnant women.
Environmental research - 15 Mar 2023
Liang Xiaoshan, Guo Guanshuai, Wang Yiyun, Wang Meng, Chen Xi, Zhang Jingran, Li Shuying, Liu Liangpo, Huang Qingyu, Cui Bo, Zhang Ming, Sun Guifan, Tang Naijun, Zhang Xumei, Zhang Qiang
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in N6AMT1 and AS3MT are associated with arsenic (As) metabolism, and efficient As methylation capacity has been associated with diabetes. However, little is known about the gene-As interaction on gestational diabetes mellitus (GDM). OBJECTIVE: This study aimed to explore the individual and combined effects of N6AMT1 and AS3MT SNPs with As metabolism on GDM....
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