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Urinary arsenic metabolism, genetic susceptibility, and their interaction on type 2 diabetes.

Chemosphere - 1 Dec 2023

Li Weiya, Li Zhaoyang, Yan Yan, Zhang Jiazhen, Zhou Qihang, Jia Chengyong, Xu Yali, Cui Hongsheng, Xie Shenglan, Liu Qianying, Guan Youbing, Liu Yuenan, He Meian

Abstract excerpt

Growing studies investigated the association of arsenic metabolism with type 2 diabetes (T2D), however, the epidemiological evidence is inconsistent. In addition, the interaction of arsenic metabolism-related genetic risk score (GRS)-arsenic on T2D risk was unclear. The present study aimed to evaluate the association of arsenic metabolism efficiency [inorganic arsenic (iAs)%, monomethylarsonic acid (MMA)%, and...

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PMID: 37890798
DOI: 10.1016/j.chemosphere.2023.140536

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