Article
Sample size determination for studies of gene-environment interaction.
International journal of epidemiology - 1 Oct 2001
Luan J A, Wong M Y, Day N E, Wareham N J
Abstract excerpt
BACKGROUND: The search for interaction effects is common in epidemiological studies, but the power of such studies is a major concern. This is a practical issue as many future studies will wish to investigate potential gene-gene and gene-environment interactions and therefore need to be planned on the basis of appropriate sample size calculations. METHODS: The underlying model considered in this paper is a simple...
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