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Article

A Single Nucleotide Polymorphism rs1010816 Predicts Sorafenib Therapeutic Outcomes in Advanced Hepatocellular Carcinoma.

International journal of molecular sciences - 14 Jan 2023

Lin Chih-Lang, Liang Kung-Hao, Hu Ching-Chih, Chien Cheng-Hung, Chen Li-Wei, Chien Rong-Nan, Lin Yang-Hsiang, Yeh Chau-Ting

Abstract excerpt

Sorafenib is currently a targeted agent widely used in the treatment of advanced hepatocellular carcinoma (aHCC). However, to date there is still a lack of a reliable marker capable of predicting sorafenib therapeutic responses. Here, we conducted a genome-wide association study (GWAS) to identify candidate single-nucleotide polymorphism outcome predictors in aHCC patients. A total of 74 real-world...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36675198
DOI: 10.3390/ijms24021681
PMCID: PMC9862766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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