Article
A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach.
Diabetes - 1 Feb 2023
Garfield Victoria, Salzmann Antoine, Burgess Stephen, Chaturvedi Nish
Abstract excerpt
In this study we examine the instrument selection strategies currently used throughout the type 2 diabetes and HbA1c Mendelian randomization (MR) literature. We then argue for a more integrated and thorough approach, providing a framework to do this in the context of HbA1c and diabetes. We conducted a literature search for MR studies that have instrumented diabetes and/or HbA1c. We also used data from the UK...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.