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Article

Causal association between antidiabetic drug targets and risk of Bell's palsy: A 2-sample Mendelian randomization study.

Medicine - 17 Jul 2026

Lu Kaifu, Ye Linlin, Yi Xuelian, He Yuxin

Abstract excerpt

To investigate the causal effects of antidiabetic drug targets on Bell's palsy risk using Mendelian randomization (MR), addressing limitations of observational studies and informing therapeutic strategies for diabetic patients. A 2-sample MR analysis was conducted using genetic instruments for 5 major antidiabetic drug classes: sulfonylureas (ABCC8/KCNJ11), metformin (GPD1), thiazolidinediones (PPARG), GLP1-RAs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42470027
DOI: 10.1097/MD.0000000000049559
PMCID: PMC13384540

Genes

ABCC8
GPD1
KCNJ11
GLP1R
PPARG
SLC5A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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