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Article

Calorie restriction alters the mechanisms of radiation-induced mouse thymic lymphomagenesis.

PloS one - 1 Jan 2023

Nakayama Takafumi, Sunaoshi Masaaki, Shang Yi, Takahashi Mizuki, Saito Takato, Blyth Benjamin J, Amasaki Yoshiko, Daino Kazuhiro, Shimada Yoshiya, Tachibana Akira, Kakinuma Shizuko

Abstract excerpt

Calorie restriction (CR) suppresses not only spontaneous but also chemical- and radiation-induced carcinogenesis. Our previous study revealed that the cancer-preventive effect of CR is tissue dependent and that CR does not effectively prevent the development of thymic lymphoma (TL). We investigated the association between CR and the genomic alterations of resulting TLs to clarify the underlying resistance...

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Identifiers

PMID: 36662808
DOI: 10.1371/journal.pone.0280560
PMCID: PMC9858762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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