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Article

Short-term serial circulating tumor DNA assessment predicts therapeutic efficacy for patients with advanced pancreatic cancer.

Journal of cancer research and clinical oncology - 26 Jan 2024

Motobayashi Hideki, Kitahata Yuji, Okada Ken-Ichi, Miyazawa Motoki, Ueno Masaki, Hayami Shinya, Miyamoto Atsushi, Shimizu Atsushi, Sato Masatoshi, Yoshimura Tomohiro, Nakamura Yuki, Takemoto Norio, Nakai Tomoki, Hyo Takahiko, Matsumoto Kyohei, Yamaue Hiroki, Kawai Manabu

Abstract excerpt

PURPOSE: We investigated the potential clinical utility of short-term serial KRAS-mutated circulating cell-free tumor DNA (ctDNA) assessment for predicting therapeutic response in patients undergoing first-line chemotherapy for advanced pancreatic cancer. METHODS: We collected 144 blood samples from 18 patients with locally advanced or metastatic cancer that were undergoing initial first-line chemotherapy of...

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Identifiers

PMID: 38277079
DOI: 10.1007/s00432-023-05594-1
PMCID: PMC10817839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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