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Article

Platelet response to influenza vaccination reflects effects of aging

19 Jan 2023

Abstract excerpt

Platelets are uniquely positioned as mediators of not only hemostasis but also innate immunity. However, how age and geriatric conditions such as frailty influence platelet function during an immune response remains unclear. We assessed the platelet transcriptome at baseline and following influenza vaccination in Younger (age 21-35) and Older (age ≥65) adults (including community-dwelling individuals who were...

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PMID: 36656789
DOI: 10.1111/acel.13749

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