Article
Association of promoter methylation status of NRF2 and PNPLA3 genes in alcoholic liver disease.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Dec 2022
M K Sibin, Manrai Manish, Singh Ranveer, Mukherjee Bhasker, Mishra Yogendra, Singh Mukesh U, Singh Amandeep, Negi Rakhi, Chandra G Bala, S V Athira, Misra Pratibha
Abstract excerpt
BACKGROUND: Alcoholic liver disease (ALD) is the leading cause of chronic liver disease. In the liver, metabolism of alcohol occurs through multiple mechanisms and it results in the generation of various toxic products. Multiple genetic causes have been identified that are associated with the development and progression of ALD. The present study assessed the promoter site methylation status of nuclear factor...
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