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Identification of the genomic region under epigenetic regulation during non‐alcoholic fatty liver disease progression

23 Oct 2017

Abstract excerpt

AIM: The progression of non-alcoholic fatty liver disease (NAFLD) is affected by epigenetics. We undertook co-methylation and differentially methylated region (DMR) analyses to identify the genomic region that is under epigenetic regulation during NAFLD progression. METHODS: We collected liver biopsy specimens from 60 Japanese patients with NAFLD and classified these into mild (fibrosis stages 0-2) or advanced...

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PMID: 29059699
DOI: 10.1111/hepr.12992

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