Article
ALDH1 as a Functional Marker of Cancer Stem and Progenitor Cells
23 Jun 2008
Abstract excerpt
Stem cells have now been described in a variety of tissues, even in those where the cells' turn over rate is slow, such as the brain and the resting mammary gland. There is also accumulating evidence that tumors are derived from and are maintained by a rare population of dysregulated stem cells. However, discrepancies in the markers used and reported have slowed down the functional characterization of these...
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