Article
Embryo Selection for a Carrier of an Early-Onset Alzheimer's Disease-Associated Mutation in the PSEN1 Gene.
The journal of prevention of Alzheimer's disease - 1 Jan 2023
Valdés-Martínez O H, García-Luna S M, Oceguera-Palao L C, Villarreal-Pineda L, Sordia-Hernández L H, de la Fuente Cortez B, Morales-Martínez A
Abstract excerpt
Alzheimer's disease (AD) is the most common neurodegenerative dementia. It manifests as early-onset or late-onset AD. Early-onset AD represents about 5.5% of the total cases and occurs in patients under age 65. The EOAD progresses more aggressively and has a shorter life expectancy due to a greater pathogenic load. We present two asymptomatic siblings, a 30-year-old male and a 34- year-old female, who are...
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