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Article

CYP2C9 polymorphism is associated with susceptibility to ischemic stroke in a Chinese population.

Annals of medicine - 1 Dec 2025

Zhang Jinglu, Jia Haiyu, Liu Yun, Zhang Yong, Nie Haihong, Bao Qiuhong

Abstract excerpt

OBJECTIVE: Ischemic stroke (IS) is a global cerebrovascular disease with high morbidity and mortality. CYP2C9 genetic variants are significantly involved in the development of many diseases. However, the impacts that CYP2C9 genetic variants on the risk of IS remain to be comprehensively understood. We aim to determine the association of CYP2C9 with IS susceptibility in the Chinese Han population. METHODS: This...

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Topics

Aged
Female
Humans
Male
Middle Aged
Case-Control Studies
China

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cytochrome P-450 CYP2C9

East Asian People

Genetic Predisposition to Disease

Genotype

Haplotypes

Ischemic Stroke

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41165008
DOI: 10.1080/07853890.2025.2579788
PMCID: PMC12576905

Genes

CYP2C9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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