Effect of interleukin-17 on periodontitis development: An instrumental variable analysis.

doi:10.1002/JPER.22-0365

Article

Effect of interleukin-17 on periodontitis development: An instrumental variable analysis.

Journal of periodontology - 1 May 2023

Baumeister Sebastian-Edgar, Holtfreter Birte, Lars Reckelkamm Stefan, Hagenfeld Daniel, Kocher Thomas, Alayash Zoheir, Ehmke Benjamin, Baurecht Hansjörg, Nolde Michael

Abstract excerpt

BACKGROUND: Circulating levels of interleukin-17 (IL-17) are associated with the presence and severity of periodontitis. However, whether IL-17 is causal for disease development is unknown. We investigated the effect of genetically proxied IL-17 on periodontitis using instrumental variable analys...

Topics

Humans
Interleukin-17
Genome-Wide Association Study
Polymorphism, Single Nucleotide
Periodontitis

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