Impact of IL-17A rs2275913 allelic variation on periodontitis susceptibility: evidence from a meta-analysis.

doi:10.1007/s10266-025-01220-3

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Article

Impact of IL-17A rs2275913 allelic variation on periodontitis susceptibility: evidence from a meta-analysis.

Odontology - 1 Jul 2026

Zhang Jiawei, Xu Shulan

Abstract excerpt

Interleukin-17A (IL-17A) plays a vital immunomodulatory role in periodontal disease. While the IL-17A rs2275913 polymorphism has been investigated for its potential influence on periodontitis risk, reported associations remain inconsistent. To conduct a systematic review and meta-analysis evaluat...

Topics

Humans
Interleukin-17
Genetic Predisposition to Disease
Periodontitis
Alleles
Polymorphism, Single Nucleotide
Case-Control Studies

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