Article
Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria.
Mediators of inflammation - 1 Jan 2016
Borilova Linhartova Petra, Kastovsky Jakub, Lucanova Svetlana, Bartova Jirina, Poskerova Hana, Vokurka Jan, Fassmann Antonin, Kankova Katerina, Izakovicova Holla Lydie
Abstract excerpt
Interleukin-17 contributes to the pathogenesis of type 1 diabetes mellitus (T1DM) and chronic periodontitis (CP). We analyzed IL-17A -197A/G and IL-17F +7488C/T polymorphisms in T1DM and CP and determined their associations with IL-17 production and occurrence of periopathogens. Totally 154 contr...
Topics
- Adult
- Alleles
- Case-Control Studies
- Chronic Periodontitis
- Diabetes Mellitus, Type 1
- Female
- Gene Frequency
- Genotype
- Humans
- Interleukin-17
- Leukocytes, Mononuclear
- Male
- Middle Aged
- Polymorphism, Single Nucleotide