Article
Inhibition of tumor necrosis factor receptor 1 and the risk of periodontitis.
Frontiers in immunology - 1 Jan 2023
Alayash Zoheir, Baumeister Sebastian-Edgar, Holtfreter Birte, Kocher Thomas, Baurecht Hansjörg, Ehmke Benjamin, Reckelkamm Stefan Lars, Nolde Michael
Abstract excerpt
Aim: To investigate the effect of genetically proxied inhibition of tumor necrosis factor receptor 1 (TNFR1) on the risk of periodontitis. Materials and methods: Genetic instruments were selected from the vicinity of TNFR superfamily member 1A (TNFRSF1A) gene (chromosome 12; base pairs 6,437,923-6,451,280 as per GRCh37 assembly) based on their association with C-reactive protein (N= 575,531). Summary statistics...
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