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Article

Novel FSIP2 Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in Humans

19 Dec 2022

Abstract excerpt

Asthenoteratozoospermia is one of the major factors for male infertility, whereas the causes of large numbers of cases are still unknown. We identified compound heterozygous variants of FSIP2 in three unrelated individuals from a cohort of 105 patients with asthenoteratozoospermia by exome sequencing. Deleterious FSIP2 variations caused severe disassembly of the fibrous sheath and axonemal defects. Intriguingly,...

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PMID: 36632462
DOI: 10.7150/ijbs.76051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Novel FSIP2 Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in HumansPMID 36632462Read ↗

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