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Article

High polymorphism in MHC-DRB genes in golden snub-nosed monkeys reveals balancing selection in small, isolated populations.

BMC evolutionary biology - 13 Mar 2018

Zhang Pei, Huang Kang, Zhang Bingyi, Dunn Derek W, Chen Dan, Li Fan, Qi Xiaoguang, Guo Songtao, Li Baoguo

Abstract excerpt

BACKGROUND: Maintaining variation in immune genes, such as those of the major histocompatibility complex (MHC), is important for individuals in small, isolated populations to resist pathogens and parasites. The golden snub-nosed monkey (Rhinopithecus roxellana), an endangered primate endemic to China, has experienced a rapid reduction in numbers and severe population fragmentation over recent years. For this...

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Identifiers

PMID: 29534675
DOI: 10.1186/s12862-018-1148-7
PMCID: PMC5851093

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