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Article

The causality between C-reactive protein and asthma: a two-sample Mendelian randomization analysis.

Postgraduate medical journal - 18 Jul 2024

Mou Yong, Cao Wenhao, Wang Rujuan, Liu Xiaofan, Yang Xiuwen, Zhu Jing

Abstract excerpt

PURPOSE: This study sought to investigate the causal effects of circulating C-reactive protein (CRP) level on risk of asthma and its subtypes by two-sample Mendelian randomization (MR) analysis. METHODS: We utilized single nucleotide polymorphisms (SNPs) associated with both CRP and outcomes of asthma, allergic asthma, and obesity-related asthma as genetic variables via a genome-wide summary association study...

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Asthma
C-Reactive Protein
Causality
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 38490259
DOI: 10.1093/postmj/qgae019

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