Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model.

Microbiological research - 1 Mar 2023

Kahlert Christian R, Nigg Susanne, Onder Lucas, Dijkman Ronald, Diener Liliane, Vidal Ana G Jop, Rodriguez Regulo, Vernazza Pietro, Thiel Volker, Vidal Jorge E, Albrich Werner C

Abstract excerpt

BACKGROUND: The effects of the com quorum sensing system during colonisation and invasion of Streptococcus pneumoniae (Spn) are poorly understood. METHODS: We developed an ex vivo model of differentiated human airway epithelial (HAE) cells with beating ciliae, mucus production and tight junctions to study Spn colonisation and translocation. HAE cells were inoculated with Spn wild-type TIGR4 (wtSpn) or its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Phenotype
Share to Quorum Sensing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Streptococcus pneumoniae

Source

Open in PubMed Open full text

Identifiers

PMID: 36608536
DOI: 10.1016/j.micres.2022.127297
PMCID: PMC9868095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model.PMID 36608536Read ↗

The quorum sensing <i>com</i> system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue modelSemantic proximity Read ↗

Airway Epithelial Cell Integrity Protects from Cytotoxicity of <i>Pseudomonas aeruginosa</i> Quorum-Sensing SignalsSemantic proximity Read ↗

Coexistence of two divergent TprA/PhrA cell-cell communication systems in <i>Streptococcus mitis</i> coordinate bacteriocin production, competence, oxidative stress responses, and interspecies competition with <i>S. pneumoniae</i>Semantic proximity Read ↗

Epithelial micro-invasion by <i>Streptococcus pneumoniae</i> induces epithelial-derived innate immunity during colonisation at the human mucosal surfaceSemantic proximity Read ↗

Modelling persistentMycoplasma pneumoniaeinfection of human airway epitheliumSemantic proximity Read ↗

Mathematical Modeling of Streptococcus pneumoniae Colonization, Invasive Infection and TreatmentSemantic proximity Read ↗

Inhibitory effect of capsule on natural transformation of <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Current concepts on Pseudomonas aeruginosa interaction with human airway epitheliumSemantic proximity Read ↗

Pneumococcal quorum sensing drives an asymmetric owner–intruder competitive strategy during carriage via the competence regulonSemantic proximity Read ↗

Inhibitory effect of capsule on natural transformation of Streptococcus pneumoniaeSemantic proximity Read ↗

Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunitySemantic proximity Read ↗

Interkingdom Signaling Induces Streptococcus pneumoniae Biofilm Dispersion and Transition from Asymptomatic Colonization to DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.