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Genetic, Surgical and Oncological Approach to Breast Cancer, with BRCA1, BRCA2, CDH1, PALB2, PTEN and TP53 Variants

27 Dec 2022

Abstract excerpt

The aim of this study was to determine the frequency of germline variants in BRCA1, BRCA2, CDH1, PALB2, PTEN and TP53 in patients admitted to a medical genetics clinic with breast cancer and to assess these identified variants according to published genetic, surgical and oncological perspectives. Materials and Methods: Medical history, and cancer diagnosis information for 195 independent probands with operated...

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PMID: 36605468
DOI: 10.4274/ejbh.galenos.2022.2022-7-2

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