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Pan-cancer analysis of necroptosis-related gene signature for the identification of prognosis and immune significance

21 Mar 2022

Abstract excerpt

BACKGROUND: Necroptosis is a novel programmed cell death mode independent on caspase. A number of studies have revealed that the induction of necroptosis could act as an alternative therapeutic strategy for drug-resistant tumors as well as affect tumor immune microenvironment. METHODS: Gene expression profiles and clinical data were downloaded from XENA-UCSC (including The Cancer Genome Atlas and Genotype-Tissue...

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PMID: 35312867
DOI: 10.1007/s12672-022-00477-2

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