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Article

Turning up the heat on non-immunoreactive tumors: pyroptosis influences the tumor immune microenvironment in bladder cancer.

Oncogene - 1 Nov 2021

Chen Xingyu, Chen Haotian, Yao Honghui, Zhao Kai, Zhang Yao, He Dong, Zhu Yuxing, Cheng YaXin, Liu Rui, Xu Runshi, Cao Ke

Abstract excerpt

The latest research confirms that cytotoxic lymphocytes rely on pyroptosis to kill tumor cells, suggesting that pyroptosis plays a vital role in immune response. However, the influence of pyroptosis on tumor microenvironment (TME) remodeling and immunotherapy is still unclear. We analyzed the variations in the expression of 28 pyroptosis-related molecules in pan-cancer tissues and normal tissues and the influence...

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Source

Identifiers

PMID: 34588621
DOI: 10.1038/s41388-021-02024-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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