Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy.

Aging - 17 Aug 2023

Huang Kaida, Lin Yubiao, Qiu Guoqin, Wang Shengyu, Feng Lihua, Zheng Zhigao, Gao Yingqin, Fan Xin, Zheng Wenhui, Zhuang Jianmin, Luo Fanghong, Feng Shuitu

Abstract excerpt

OBJECTIVE: Pyroptosis is a form of programmed cell death that is essential for immunity. Herein, this study was conducted to uncover the implication of pyroptosis in immunomodulation and tumor microenvironment (TME) in gastric cancer. METHODS: Prognostic pyroptosis-related genes were extracted to identify different pyroptosis phenotypes and pyroptosis genomic phenotypes via unsupervised clustering analysis in the...

Topics

Join the communities discussing this publication.

Immunomodulation
Immunotherapy
Phenotype
Stomach Neoplasms
Tumor Microenvironment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 37595258
DOI: 10.18632/aging.204958
PMCID: PMC10497016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy.PMID 37595258Read ↗

Pyroptosis Patterns Characterized by Distinct Tumor Microenvironment Infiltration Landscapes in Gastric CancerSemantic proximity Read ↗

Establishment and Systematic Evaluation of Gastric Cancer Classification Model Based on PyroptosisSemantic proximity Read ↗

Pan-Cancer Analyses of Pyroptosis With Functional Implications in Prognosis and Immunotherapy in CancerSemantic proximity Read ↗

Identification and Validation of a Pyroptosis-Related Prognostic Model for Gastric CancerSemantic proximity Read ↗

Predicting the Prognosis of Esophageal Adenocarcinoma by a Pyroptosis-Related Gene SignatureSemantic proximity Read ↗

Identification of the Novel Pyroptosis-Related Gene Signature in Patients with Esophageal AdenocarcinomaSemantic proximity Read ↗

Development and validation of a necroptosis-related gene prognostic score to predict prognosis and efficiency of immunotherapy in gastric cancerSemantic proximity Read ↗

Multi-omics features of immunogenic cell death in gastric cancer identified by combining single-cell sequencing analysis and machine learningSemantic proximity Read ↗

The Pyroptosis-Related Signature Predicts Prognosis and Indicates New Treatment Targets in Pancreatic CancerSemantic proximity Read ↗

A novel prognostic and therapeutic target biomarker based on necroptosis-related gene signature and immune microenvironment infiltration in gastric cancerSemantic proximity Read ↗

Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspectiveSemantic proximity Read ↗

Construction of a novel signature and prediction of the immune landscape in gastric cancer based on necroptosis-related genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.