Article
fmr1 Mutation Alters the Early Development of Sensory Coding and Hunting and Social Behaviors in Larval Zebrafish.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Feb 2023
Zhu Shuyu I, McCullough Michael H, Pujic Zac, Sibberas Jordan, Sun Biao, Darveniza Thomas, Bucknall Bianca, Avitan Lilach, Goodhill Geoffrey J
Abstract excerpt
Autism spectrum disorders (ASDs) are developmental in origin; however, little is known about how they affect the early development of behavior and sensory coding. The most common inherited form of autism is Fragile X syndrome (FXS), caused by a mutation in FMR1 Mutation of fmr1 in zebrafish causes anxiety-like behavior, hyperactivity, and hypersensitivity in auditory and visual processing. Here, we show that...
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