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Article

Pleiotropic contribution of rbfox1 to psychiatric and neurodevelopmental phenotypes in two zebrafish models.

Translational psychiatry - 19 Feb 2024

Antón-Galindo Ester, Adel Maja R, García-González Judit, Leggieri Adele, López-Blanch Laura, Irimia Manuel, Norton William H J, Brennan Caroline H, Fernàndez-Castillo Noèlia, Cormand Bru

Abstract excerpt

RBFOX1 is a highly pleiotropic gene that contributes to several psychiatric and neurodevelopmental disorders. Both rare and common variants in RBFOX1 have been associated with several psychiatric conditions, but the mechanisms underlying the pleiotropic effects of RBFOX1 are not yet understood. Here we found that, in zebrafish, rbfox1 is expressed in spinal cord, mid- and hindbrain during developmental stages. In...

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Identifiers

PMID: 38374212
DOI: 10.1038/s41398-024-02801-6
PMCID: PMC10876957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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