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Innate lymphoid cells: from helper to killer

21 Sept 2020

Abstract excerpt

Five subsets of ILCs are extensively described, Lymphoid Tissue inducer (LTi) cells, cytotoxic NK cells and non-cytotoxic helper ILC1s, ILC2s and ILC3s. So far, the main focus has been on the potent cytokine production by helper ILCs and their plastic nature that allows them to switch function and phenotype upon environmental changes. Recent advances in the field indicate the presence of cytotoxic helper ILCs...

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PMID: 32971468
DOI: 10.1016/j.coi.2020.08.007

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