Article
Functional and Molecular Characters of Cancer Stem Cells Through Development to Establishment.
Advances in experimental medicine and biology - 1 Jan 2022
Afify Said M, Hassan Ghmkin, Ishii Hiroko, Monzur Sadia, Nawara Hend M, Osman Amira, Abu Quora Hagar A, Sheta Mona, Zahra Maram H, Seno Akimasa, Seno Masaharu
Abstract excerpt
Cancer stem cells (CSCs) are small subpopulation sharing similar properties like normal stem such as self-renewal and differentiation potential to direct tumor growth. Last few years, scientists considered CSCs as the cause of phenotypic heterogeneity in diverse cancer types. Also, CSCs contribute to cancer metastasis and recurrence. The cellular and molecular regulators influence on the CSCs' phenotype changing...
Topics
- Humans
- Neoplasms
- Neoplastic Stem Cells
- Cell Differentiation
- Phenotype
- Tumor Microenvironment