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An Overview of Concepts for Cancer Stem Cells

7 Dec 2010

Abstract excerpt

For many years, cancer research has focused on the adult stem cells present in malignant tumors. It is believed that current cancer treatments sometimes fail because they do not target these cells. According to classic models of carcinogenesis, these events can occur in any cell. In contrast, the cancer stem cell (CSC) hypothesis states that the preferential targets of oncogenic transformation are tissue stem...

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PMID: 20887682
DOI: 10.3727/096368910x532837

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