Article
Isolation, identification, and characterization of cancer stem cells: A review.
Journal of cellular physiology - 1 Aug 2017
Abbaszadegan Mohammad Reza, Bagheri Vahid, Razavi Mahya Shariat, Momtazi Amir Abbas, Sahebkar Amirhossein, Gholamin Mehran
Abstract excerpt
Cancer stem cells (CSCs) or tumor-initiating cells (TICs) as a small subset of neoplastic cells are able to produce a tumor (tumorigenesis), maintain the population of tumorigenic cells (self-renewal), and generate the heterogeneous cells constructing the entire tumor (pluripotency). The research on stationary and circulating CSCs due to resistance to conventional therapies and inability in complete eradication...
Topics
- Animals
- Antineoplastic Agents
- Biomarkers, Tumor
- Cell Movement
- Cell Self Renewal
- Cell Separation
- Drug Resistance, Neoplasm
- Humans
- Neoplasm Metastasis
- Neoplasms
- Neoplastic Cells, Circulating