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The Implications of Cancer Stem Cells for Cancer Therapy

5 Dec 2012

Abstract excerpt

Surgery, radiotherapy and chemotherapy are universally recognized as the most effective anti-cancer therapies. Despite significant advances directed towards elucidating molecular mechanisms and developing clinical trials, cancer still remains a major public health issue. Recent studies have showed that cancer stem cells (CSCs), a small subpopulation of tumor cells, can generate bulk populations of nontumorigenic...

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PMID: 23443123
DOI: 10.3390/ijms131216636

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