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Article

Biomarker-driven drug repurposing on biologically similar cancers with DNA-repair deficiencies

13 Dec 2022

Abstract excerpt

Similar molecular and genetic aberrations among diseases can lead to the discovery of jointly important treatment options across biologically similar diseases. Oncologists closely looked at several hormone-dependent cancers and identified remarkable pathological and molecular similarities in their DNA repair pathway abnormalities. Although deficiencies in Homologous Recombination (HR) pathway plays a significant...

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PMID: 36583025
DOI: 10.3389/fgene.2022.1015531

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