Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular senescence in cancer: clinical detection and prognostic implications

27 Dec 2022

Abstract excerpt

Cellular senescence is a state of stable cell-cycle arrest with secretory features in response to cellular stress. Historically, it has been considered as an endogenous evolutionary homeostatic mechanism to eliminate damaged cells, including damaged cells which are at risk of malignant transformation, thereby protecting against cancer. However, accumulation of senescent cells can cause long-term detrimental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced biosensing and bioanalysis techniques
Share to Single-cell and spatial transcriptomics
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36575462
DOI: 10.1186/s13046-022-02555-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular senescence in cancer: clinical detection and prognostic implicationsPMID 36575462Read ↗

Cellular senescence: a double-edged sword in cancer therapySemantic proximity Read ↗

Cellular senescence in cancerSemantic proximity Read ↗

A guide to assessing cellular senescence in vitro and in vivoSemantic proximity Read ↗

The Jekyll and Hyde of Cellular Senescence in CancerSemantic proximity Read ↗

Cellular Senescence: The Sought or the Unwanted?Semantic proximity Read ↗

Exploiting tumor cell senescence in anticancer therapySemantic proximity Read ↗

The dual role of cellular senescence in human tumor progression and therapySemantic proximity Read ↗

Hallmarks of cellular senescence: biology, mechanisms, regulationsSemantic proximity Read ↗

Cellular senescence in cancer: from mechanisms to detection.Semantic proximity Read ↗

Cellular Senescence as a Target in Cancer ControlSemantic proximity Read ↗

Therapy-Induced Senescence: Novel Approaches for Markers IdentificationSemantic proximity Read ↗

Regulation of cellular senescence in tumor progression and therapeutic targeting: mechanisms and pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.