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Article

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective.

Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2026

Cazzaniga Alessandra, Frigo Silvia, Cherubini Alessandro, Rrapaj Eniada, Valenti Luca

Abstract excerpt

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality control-namely impaired autophagy-as central mechanisms governing...

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Source

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Identifiers

PMID: 42522599
DOI: 10.1111/liv.70816
PMCID: PMC13417050

Genes

ATG7
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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