Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagy and adipogenesis: Implications in obesity and type II diabetes

1 Jan 2010

Abstract excerpt

Obesity is a direct result of the accumulation of white adipose tissue (WAT). In this study, the role of autophagy in the differentiation of white adipose tissue was studied by deleting the autophagy-related 7 (atg7) gene from adipose tissue in mice. This deletion results in a striking phenotype at the cellular, tissue and whole-organism levels. Adipose tissue deposits in the mutant mice are much smaller in mass...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Autophagy in Disease and Therapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20110772
DOI: 10.4161/auto.6.1.10814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy and adipogenesis: Implications in obesity and type II diabetesPMID 20110772Read ↗

Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseasesSemantic proximity Read ↗

Role of Autophagy in the Control of Body MetabolismSemantic proximity Read ↗

Autophagy in Adipose TissueSemantic proximity Read ↗

Asprosin contributes to pathogenesis of obesity by adipocyte mitophagy induction to inhibit white adipose browning in miceSemantic proximity Read ↗

Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse modelSemantic proximity Read ↗

<i>Slc7a8</i> deletion is protective against diet-induced obesity and attenuates lipid accumulation in multiple organsSemantic proximity Read ↗

Slc7a8 Deletion Is Protective against Diet-Induced Obesity and Attenuates Lipid Accumulation in Multiple OrgansSemantic proximity Read ↗

Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.Semantic proximity Read ↗

Targeting Autophagy in Obesity‐Associated Heart DiseaseSemantic proximity Read ↗

Unmasking the janus faces of autophagy in obesity‐associated insulin resistance and cardiac dysfunctionSemantic proximity Read ↗

Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance.Semantic proximity Read ↗

Role of autophagy in diabetes and mitochondria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.