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Article

Causal association between systemic lupus erythematosus and the risk of dementia: A Mendelian randomization study

8 Dec 2022

Abstract excerpt

Introduction: It is well-documented that systemic lupus erythematosus (SLE) is associated with dementia. However, the genetic causality of this association remains unclear. Mendelian randomization (MR) was used to investigate the potential causal relationship between SLE and dementia risk in the current study. Methods: We selected 45 single nucleotide polymorphisms (SNPs) associated with SLE from publicly...

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PMID: 36569847
DOI: 10.3389/fimmu.2022.1063110

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