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Single-cell RNA sequencing reveals resident progenitor and vascularization-associated cell subpopulations in rat annulus fibrosus

8 Dec 2022

Abstract excerpt

One of the main causes of low back pain is intervertebral disc degeneration (IDD). Annulus fibrosus (AF) is important for the integrity and functions of the intervertebral disc (IVD). However, the resident functional cell components such as progenitors and vascularization-associated cells in AF are yet to be fully identified. Identification of functional AF cell subpopulations including resident progenitors and...

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PMID: 36568849
DOI: 10.1016/j.jot.2022.11.004

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