Article
The Association between Symptomatic Rotavirus Infection and Histo-Blood Group Antigens in Young Children with Diarrhea in Pretoria, South Africa.
Viruses - 8 Dec 2022
Rakau Kebareng, Gededzha Maemu, Peenze Ina, Huang Pengwei, Tan Ming, Steele Andrew Duncan, Seheri Luyanda Mapaseka
Abstract excerpt
OBJECTIVES: Recently, histo-blood group antigens (HBGAs) have been identified as receptors or attachment factors of several viral pathogens. Among rotaviruses, HBGAs interact with the outer viral protein, VP4, which has been identified as a potential susceptibility factor, although the findings are inconsistent throughout populations due to HBGA polymorphisms. We investigated the association between HBGA...
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