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Histo-blood group antigens and rotavirus vaccine virus shedding in Australian infants.

Pathology - 1 Dec 2022

El-Heneidy Asmaa, Cheung Catherine, Lambert Stephen B, Wang Claire Y T, Whiley David M, Sly Peter D, Ware Robert S, Grimwood Keith

Abstract excerpt

Rotavirus vaccine performance varies between high and low income countries. One possible explanation is inherited histo-blood group antigens (HBGAs) the expression of which differs between populations. HBGAs are polymorphic glycans on mucosal surfaces. Their presence indicates the secretor phenotype, while their absence identifies a non-secretor status. HBGAs can act as rotavirus receptors and might influence...

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PMID: 35817636
DOI: 10.1016/j.pathol.2022.04.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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