Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Both Lewis and secretor status mediate susceptibility to rotavirus infections in a rotavirus genotype-dependent manner.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Dec 2014

Nordgren Johan, Sharma Sumit, Bucardo Filemon, Nasir Waqas, Günaydın Gökçe, Ouermi Djeneba, Nitiema Leon W, Becker-Dreps Sylvia, Simpore Jacques, Hammarström Lennart, Larson Göran, Svensson Lennart

Abstract excerpt

BACKGROUND: The live oral rotavirus (RV) vaccines have shown a reduced efficacy in Africa. Recent in vitro studies have shown binding of the RV surface protein (VP4) to histo-blood group antigens (HBGAs) in an RV genotype-dependent manner, suggesting them to be putative receptors for RV. The dive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ABO Blood-Group System
Share to Burkina Faso

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Infant, Newborn

Share to Lewis Blood Group Antigens

Share to Nicaragua

Share to Rotavirus

Share to Rotavirus Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 25097083
DOI: 10.1093/cid/ciu633
PMCID: PMC4650770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25097083-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Both Lewis and secretor status mediate susceptibility to rotavirus infections in a rotavirus genotype-dependent manner.PMID 25097083Read ↗

Histo-Blood Group Antigen Phenotype Determines Susceptibility to Genotype-Specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy.Semantic proximity Read ↗

The Association between Symptomatic Rotavirus Infection and Histo-Blood Group Antigens in Young Children with Diarrhea in Pretoria, South Africa.Semantic proximity Read ↗

The Lewis A phenotype is a restriction factor for Rotateq and Rotarix vaccine-take in Nicaraguan children.Semantic proximity Read ↗

Host genetic factors affect susceptibility to norovirus infections in Burkina Faso.Semantic proximity Read ↗

Nonsecretor Histo–blood Group Antigen Phenotype Is Associated With Reduced Risk of Clinical Rotavirus Vaccine Failure in Malawian InfantsSemantic proximity Read ↗

Human Neonatal Rotavirus Vaccine (RV3-BB) Produces Vaccine Take Irrespective of Histo-Blood Group Antigen StatusSemantic proximity Read ↗

Histo-Blood Group Antigen Null Phenotypes Associated With a Decreased Risk of Clinical Rotavirus Vaccine Failure Among Children <2 Years of Age Participating in the Vaccine Impact on Diarrhea in Africa (VIDA) Study in Kenya, Mali, and the Gambia.Semantic proximity Read ↗

Histo-blood group antigen profile of Australian Aboriginal children and seropositivity following oral rotavirus vaccination.Semantic proximity Read ↗

Histo-blood Group Antigen status of Australian Aboriginal children and seropositivity following oral rotavirus vaccinationSemantic proximity Read ↗

Host Genetic Susceptibility to Enteric Viruses: A Systematic Review and Metaanalysis.Semantic proximity Read ↗

FUT2 Secretor Status Influences Susceptibility to VP4 Strain-Specific Rotavirus Infections in South African ChildrenSemantic proximity Read ↗

The Impact of Human Genetic Polymorphisms on Rotavirus Susceptibility, Epidemiology, and Vaccine Take.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.