Article
Histo-blood group antigen profile of Australian Aboriginal children and seropositivity following oral rotavirus vaccination.
Vaccine - 1 Jun 2023
Middleton Bianca F, Danchin Margie, Cunliffe Nigel A, Jones Mark A, Boniface Karen, Kirkwood Carl D, Gallagher Sarah, Kirkham Lea-Ann, Granland Caitlyn, McNeal Monica, Donato Celeste, Bogdanovic-Sakran Nada, Handley Amanda, Bines Julie E, Snelling Thomas L
Abstract excerpt
BACKGROUND: Histo-blood group antigens (HBGAs) may influence immune responses to rotavirus vaccination. METHODS: HBGA phenotyping was determined by detection of antigens A, B, H and Lewis a and b in saliva using enzyme-linked immunosorbent assay. Secretor status was confirmed by lectin antigen assay if A, B and H antigens were negative or borderline (OD ± 0.1 of threshold of detection). PCR-RFLP analysis was used...
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