Article
Upregulated MYC expression and p53 mutations may contribute to the oncogenesis of canine Meibomian gland carcinomas.
Veterinary pathology - 1 Mar 2023
Peterson Cornelia, Hicks J L, De Marzo A M, Campbell A A, Eberhart C G, Dubielzig R R, Teixeira L B
Abstract excerpt
Sebaceous carcinomas of the human ocular adnexa commonly exhibit pagetoid spread, mutations in tumor-suppressor genes, and protooncogene copy number gain. Sebaceous carcinomas are rarely reported in other species, and while the Meibomian gland (MG) represents the most common ocular adnexal structure of the canine eyelid to develop neoplasia, most are clinically and histologically benign. The objective of this...
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