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Article

Establishment of canine mammary gland tumor cell lines harboring PI3K/Akt activation as a therapeutic target

28 May 2024

Abstract excerpt

Canine mammary gland tumors (MGT) have a poor prognosis in intact female canines, posing a clinical challenge. This study aimed to establish novel canine mammary cancer cell lines from primary tumors and characterize their cellular and molecular features to find potential therapeutic drugs. The MGT cell lines demonstrated rapid cell proliferation and colony formation in an anchorage-independent manner. Vimentin...

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PMID: 38807154
DOI: 10.1186/s12917-024-04085-w

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