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Article

Melatonin promotes microglia toward anti-inflammatory phenotype after spinal cord injury.

International immunopharmacology - 1 Jan 2023

Guo Yue, Zhang Peng, Zhao Haosen, Xu Chang, Lin Sen, Mei Xifan, Tian He

Abstract excerpt

Microglia, immune cells in the central nervous system (CNS), mediate inflammatory responses and provide support to the microenvironment. Neurotoxic microglia predominantly locate in the injured spinal cord that delay spinal cord injury (SCI) repair. We previously found that melatonin could suppress SCI-induced neuronal inflammatory activation. However, the effect of melatonin in microglia responses remains...

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Identifiers

PMID: 36538849
DOI: 10.1016/j.intimp.2022.109599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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