Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted deep sequencing reveals genomic alterations of actinic keratosis/cutaneous squamous cell carcinoma in situ and cutaneous squamous cell carcinoma

19 Dec 2022

Abstract excerpt

Actinic keratosis (AK) and cutaneous squamous cell carcinoma in situ (CIS) are two of the most common precursors of cutaneous squamous cell carcinoma (cSCC). However, the genomic landscape of AK/CIS and the drivers of cSCC progression remain to be elucidated. The aim of our study was to investigate the genomic alterations between AK/CIS and cSCC in terms of somatic mutations and copy number alterations (CNAs). We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Molecular Biology Techniques and Applications
Share to Nonmelanoma Skin Cancer Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36533870
DOI: 10.1111/exd.14730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted deep sequencing reveals genomic alterations of actinic keratosis/cutaneous squamous cell carcinoma in situ and cutaneous squamous cell carcinomaPMID 36533870Read ↗

Genomic Progression of Precancerous Actinic Keratosis to Squamous Cell Carcinoma.Semantic proximity Read ↗

Single-cell sequencing highlights heterogeneity and malignant progression in actinic keratosis and cutaneous squamous cell carcinomaSemantic proximity Read ↗

Single-cell Sequencing Highlights Heterogeneity and Malignant Progression in Actinic Keratosis and Cutaneous Squamous Cell CarcinomaSemantic proximity Read ↗

Mutational landscape of aggressive cutaneous squamous cell carcinoma.Semantic proximity Read ↗

The Genomic Landscape of Actinic Keratosis.Semantic proximity Read ↗

Gene expression landscape of cutaneous squamous cell carcinoma progressionSemantic proximity Read ↗

Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progressionSemantic proximity Read ↗

Invasive squamous cell carcinomas and precursor lesions on UV-exposed epithelia demonstrate concordant genomic complexity in driver genes.Semantic proximity Read ↗

From actinic keratosis to cutaneous squamous cell carcinoma: the key pathogenesis and treatmentsSemantic proximity Read ↗

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma.Semantic proximity Read ↗

Gene expression landscape of cutaneous squamous cell carcinoma progressionSemantic proximity Read ↗

Genomic progression for local invasion of cutaneous squamous cell carcinoma from the superficial to the deep portion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.