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Article

Infiltrating gliomas with FGFR alterations: Histologic features, genetic alterations, and potential clinical implications.

Cancer biomarkers : section A of Disease markers - 1 Jan 2023

Dono Antonio, El Achi Hanadi, Bundrant Bethany E, Goli Puneetha S, Zhu Ping, Ozkizilkaya Hanim I, Esquenazi Yoshua, Ballester Leomar Y

Abstract excerpt

BACKGROUND: Fibroblast growth factor receptors (FGFRs) are frequently altered in cancers and present a potential therapeutic avenue. However, the type and prevalence of FGFR alterations in infiltrating gliomas (IGs) needs further investigation. OBJECTIVE: To understand the prevalence/type of FGFR alterations in IGs. METHODS: We reviewed clinicopathologic and genomic alterations of FGFR-mutant gliomas in a cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36530080
DOI: 10.3233/CBM-220041
PMCID: PMC12412803

Genes

FGFR3
CDK4
CDKN2A
EGFR
MDM2
PTEN
TACC3
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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