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Article

Generation of two iPSC lines from long QT syndrome patients carrying SNTA1 variants.

Stem cell research - 1 Feb 2023

Jimenez-Tellez Nerea, Vera Carlos D, Yildirim Zehra, Vicente Guevara Julio, Zhang Tina, Wu Joseph C

Abstract excerpt

Long QT syndrome (LQTS) is an inherited cardiovascular disorder characterized by electrical conduction abnormalities leading to arrhythmia, fainting, seizures, and an increased risk of sudden death. There are over 15 genes involved in causing LQTS, including SNTA1. Here we generated two human-induced pluripotent stem cell (iPSC) lines from two LQT patients carrying a missense mutation in SNTA1 (c.1088A > C). Both...

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Identifiers

PMID: 36528013
DOI: 10.1016/j.scr.2022.103003
PMCID: PMC10029814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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